Impact of Zygosity on Bimodal Phenotype Distributions.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.05.010
Abstract: Allele number, or zygosity, is a clear determinant of gene expression in diploid cells. However, the relationship between the number of copies of a gene and its expression can be hard to anticipate, especially when… read more here.
Keywords: positive feedback; gene expression; zygosity; gene ... See more keywords
Gestational weight gain and neonatal outcomes in different zygosity twins: a cohort study in Wuhan, China
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-056581
Abstract: Objective To evaluate whether twin zygosity influences the association between neonatal outcomes and gestational weight gain (GWG) based on the Chinese guidelines in twin-pregnancy women. Design A retrospective cohort study. And it is not a… read more here.
Keywords: sga; lbw lbw; lbw; neonatal outcomes ... See more keywords
Evaluation of the correlation between KRAS mutated allele frequency and pathologist tumorous nuclei percentage assessment in colorectal cancer suggests a role for zygosity status
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2018-205085
Abstract: Evaluation of molecular tumour heterogeneity relies on the tumorous nuclei percentage (TNP) assessment by a pathologist, which has been criticised for being inaccurate and suffering from interobserver variability. Based on the ‘Big Bang theory’ which… read more here.
Keywords: status; nuclei percentage; tumorous nuclei; colorectal cancer ... See more keywords
“Side by side”: Development of twin relationship dimensions from early to middle childhood and the role of zygosity and parenting
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Social and Personal Relationships"
DOI: 10.1177/02654075211005857
Abstract: Twin relationships have a significant effect on the twins’ life and their families. In the first comprehensive study of this topic, our purpose was to examine the developmental courses of four dyadic dimensions of twins’… read more here.
Keywords: dependence; closeness dependence; rivalry; zygosity ... See more keywords
Rapid and precise genotyping of transgene zygosity in mice using an allele-specific method
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DOI: 10.26508/lsa.202201729
Abstract: A novel, precise, rapid, and generalizable method to determine transgene zygosity in mice by allele-specific restriction enzyme digestion of PCR products from transgenes or homologous endogenous genes. Precise determination of transgene zygosity is essential for… read more here.
Keywords: transgene zygosity; method; allele specific; mice ... See more keywords