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Anxiety Patients Show Reduced Working Memory Related dlPFC Activation During Safety and Threat

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Anxiety patients exhibit deficits in cognitive tasks that require prefrontal control of attention, including those that tap working memory (WM). However, it is unclear whether these deficits reflect threat‐related processes… Click to show full abstract

Anxiety patients exhibit deficits in cognitive tasks that require prefrontal control of attention, including those that tap working memory (WM). However, it is unclear whether these deficits reflect threat‐related processes or symptoms of the disorder. Here, we distinguish between these hypotheses by determining the effect of shock threat versus safety on the neural substrates of WM performance in anxiety patients and healthy controls.

Keywords: anxiety; anxiety patients; safety; threat; working memory

Journal Title: Depression and Anxiety
Year Published: 2017

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