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The role of bone marrow morphology in the diagnosis of relapsed acute myeloid leukemia

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We read with interest the recent article by Zhou et al.1 in Leukemia. The authors first demonstrate an almost invariably abnormal multiparameter flow cytometry (MFC) when morphologic exam shows relapse… Click to show full abstract

We read with interest the recent article by Zhou et al.1 in Leukemia. The authors first demonstrate an almost invariably abnormal multiparameter flow cytometry (MFC) when morphologic exam shows relapse in patients with acute myeloid leukemia (AML). This low false-negative rate of MFC questions the need for morphologic exam when MFC is negative and if the only question is whether the patient has relapsed.

Keywords: role bone; myeloid leukemia; leukemia role; acute myeloid; leukemia; bone marrow

Journal Title: Leukemia
Year Published: 2018

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