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Cyclometalated 1,3-bis(8-quinolyl) phenyl chloroplatinum(II) (Pt1) shows selective luminescence transduction of G-quadruplex binding over duplex DNA. The effect is enhanced on association with parallel and hybrid G-quadruplex structures over other topologies.… Click to show full abstract
Cyclometalated 1,3-bis(8-quinolyl) phenyl chloroplatinum(II) (Pt1) shows selective luminescence transduction of G-quadruplex binding over duplex DNA. The effect is enhanced on association with parallel and hybrid G-quadruplex structures over other topologies. The kinetics of binding are studied for c-myc and the response is found to be partially reversible in a displacement assay.
Keywords:
dna;
light switch;
platinum complex;
selective light;
complex selective;
cyclometalated platinum
Journal Title: Dalton transactions
Year Published: 2023
Link to full text (if available)
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Journal Title: Dalton transactions
Year Published: 2023
Link to full text (if available)
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recommendations!