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Synthesis and characterization of new pyrido-thieno-pyrimidine derivatives incorporating pyrazole moiety

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ABSTRACT 2-Hydrazinyl-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one was reacted with commercially available active methylene compounds (e.g., acetylacetone, ethyl acetoacetate, and diethyl malonate) and ethoxymethylenemalononitrile to afford the respective pyrazole derivatives. Moreover, the prepared pyrazolinone was… Click to show full abstract

ABSTRACT 2-Hydrazinyl-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one was reacted with commercially available active methylene compounds (e.g., acetylacetone, ethyl acetoacetate, and diethyl malonate) and ethoxymethylenemalononitrile to afford the respective pyrazole derivatives. Moreover, the prepared pyrazolinone was utilized for synthesis of some new arylidene-, arylazo-pyrazolinone, and azolo-triazine derivatives. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, 1H NMR, and mass spectral data. GRAPHICAL ABSTRACT

Keywords: characterization new; pyrido thieno; synthesis characterization; pyrido

Journal Title: Synthetic Communications
Year Published: 2017

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