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Malignant melanoma test results by a commercial 35‐gene expression test are enriched for benign or atypical Spitz tumors

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200, respectively), diagnosed as an epithelioid Spitz nevus, arose on the forearm of a 54-year-old man and showed a superficial plaque like, predominantly intradermal proliferation of enlarged spitzoid melanocytes arrayed… Click to show full abstract

200, respectively), diagnosed as an epithelioid Spitz nevus, arose on the forearm of a 54-year-old man and showed a superficial plaque like, predominantly intradermal proliferation of enlarged spitzoid melanocytes arrayed in small nests, cords, and single cells, with marked stromal desmoplasia and evidence of maturation. Case 2 (C, D: H&E, original magnification (cid:1) 40 and (cid:1) 200, respectively) occurred on the upper arm of a 25-year-old woman and was diagnosed as Spitz nevus. It showed a dome-shaped compound spitzoid proliferation with large superficial nests maturing to smaller single cells and cords, with evidence of maturation

Keywords: spitz; test; test results; results commercial; malignant melanoma; melanoma test

Journal Title: Journal of Cutaneous Pathology
Year Published: 2022

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