Molecular and histologic outcomes following spinal cord injury in spiny mice, Acomys cahirinus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24836
Abstract: The spiny mouse (Acomys cahirinus) appears to be unique among mammals by showing little scarring or fibrosis after skin or muscle injury, but the Acomys response to spinal cord injury (SCI) is unknown. We tested… read more here.
Keywords: molecular histologic; injury; acomys cahirinus; acomys ... See more keywords
Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.09.008
Abstract: Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell type in skin. We found that following traumatic injury to ear pinnae, MFs appeared… read more here.
Keywords: wound healing; scar free; fate; spiny mice ... See more keywords
African Spiny Mice (Acomys) Exhibit Mild Osteoarthritis Following Meniscal Injury
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DOI: 10.1177/19476035221149146
Abstract: Objective Hyaline cartilage has limited innate healing abilities and hyaline cartilage loss is a hallmark of osteoarthritis (OA). Animal models can provide important insights into cartilage regeneration potential. One such animal model, the African spiny… read more here.
Keywords: damage; meniscal injury; cartilage; hyaline cartilage ... See more keywords
Spiny mice (Acomys) cells fail to engraft in NOD scid gamma
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0286000
Abstract: Immune cells and stromal cells regulate wound healing and regeneration through complex activation patterns with spatiotemporal variation. The scarless regeneration of Spiny mice (Acomys species) is no exception; differential activation of immune and stromal cell… read more here.
Keywords: nod scid; acomys cells; spiny mice; scid gamma ... See more keywords