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Published in 2021 at "Pediatric transplantation"
DOI: 10.1111/petr.14111
Abstract: BACKGROUND CNI-free immunosuppression with conversion to mTORi-based immunosuppression has been demonstrated to reduce CNI-toxicity and to exhibit anti-proliferative properties. However, the experience of CNI-free immunosuppression in paediatric heart transplantation is limited. METHODS A retrospective analysis…
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Keywords:
free immunosuppression;
cni free;
conversion;
immunosuppression ... See more keywords
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Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281492
Abstract: Background Calcineurin inhibitors (CNIs) remain the cornerstone of maintenance immunosuppression (IS) after lung transplantation (LTx), although CNI-related life-threatening toxic effects may occur. Belatacept, a novel immunosuppressant that blocks a T-cell co-stimulation pathway, is a non-nephrotoxic…
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Keywords:
lung transplantation;
cni free;
conversion;
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Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0284653
Abstract: Background Data on calcineurin-inhibitor (CNI) free immunosuppression after lung transplantation (LTx) are limited. Aim of this study was to investigate CNI-free immunosuppression using mechanistic target of rapamycin (mTOR) inhibitors. Methods This retrospective analysis was performed…
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Keywords:
calcineurin inhibitor;
mtor inhibitors;
cni free;
free immunosuppression ... See more keywords