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Clinical Formulation Bridging of Gefapixant, a P2X3‐Receptor Antagonist, for the Treatment of Chronic Cough

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Published in 2022 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.1105

Abstract: Gefapixant is a P2X3‐receptor antagonist being developed for treatment of refractory or unexplained chronic cough. Four phase 1 studies were conducted in healthy participants that bridged the early‐phase gefapixant formulation (F01) to the phase 3… read more here.

Keywords: receptor antagonist; formulation; chronic cough; p2x3 receptor ... See more keywords