A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity
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DOI: 10.1016/j.celrep.2019.01.043
Abstract: SUMMARY The tripeptide glutathione suppresses the iron-dependent, non-apoptotic cell death process of ferroptosis. How glutathione abundance is regulated in the cell and how this regulation alters ferroptosis sensitivity is poorly understood. Using genome-wide human haploid… read more here.
Keywords: sensitivity; ferroptosis; glutathione abundance; ferroptosis sensitivity ... See more keywords