Lewis-Acid-Catalyzed Asymmetric Alkynylation of Alkynyl 1,2-Diketones: Controllable Formation of 3(2H)-Furanones and α-Hydroxy Ketones.
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DOI: 10.1021/acs.orglett.0c02505
Abstract: We report the highly regio- and enantioselective alkynylation of alkynyl 1,2-diketones under Lewis acid catalysis, leading to the formation of a series of biologically important 3(2H)-furanones with high to excellent ee values. Moreover, a slight… read more here.
Keywords: hydroxy ketones; lewis acid; alkynylation alkynyl; alkynyl diketones ... See more keywords
Synthesis of α-keto aldehydes via selective Cu(I)-catalyzed oxidation of α-hydroxy ketones.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00773h
Abstract: An efficient approach to synthesize α-keto aldehydes was established through selective oxidation of α-hydroxy ketones catalyzed by Cu(I) using oxygen as oxidant. A wide array of α-keto aldehydes was prepared with isolated yields of up… read more here.
Keywords: keto aldehydes; hydroxy ketones; oxidation hydroxy; keto ... See more keywords