Intrastriatal injection of ionomycin profoundly changes motor response to l-DOPA and its underlying molecular mechanisms
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DOI: 10.1016/j.neuroscience.2016.10.033
Abstract: Long-term l-DOPA treatment of Parkinson's disease is accompanied with fluctuations of motor responses and l-DOPA-induced dyskinesia (LID). Phosphorylation of the dopamine and c-AMP regulated phosphoprotein of 32kDa (DARPP-32) plays a role in the pathogenesis of… read more here.
Keywords: ionomycin; motor response; injection ionomycin; dopa ... See more keywords