Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation
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DOI: 10.1016/j.ebiom.2017.11.013
Abstract: Constitutive JAK-STAT signaling drives the proliferation of most myeloproliferative neoplasms (MPN) and a subset of acute myeloid leukemia (AML), but persistence emerges with chronic exposure to JAK inhibitors. MPN and post-MPN AML are dependent on… read more here.
Keywords: mediator kinase; phosphorylation; jak stat; phosphorylation stat1 ... See more keywords