High sensitivity non-invasive detection of calcifications deep inside biological tissue using Transmission Raman Spectroscopy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600260
Abstract: The aim of this research was to develop a novel approach to probe non-invasively the composition of inorganic chemicals buried deep in large volume biological samples. The method is based on advanced Transmission Raman Spectroscopy… read more here.
Keywords: raman spectroscopy; transmission raman; spectroscopy; tissue ... See more keywords
In Vivo Surface‐Enhanced Transmission Raman Spectroscopy under Maximum Permissible Exposure: Toward Photosafe Detection of Deep‐Seated Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Small Methods"
DOI: 10.1002/smtd.202201334
Abstract: The detection of deep‐seated lesions is of great significance for biomedical applications. However, due to the strong photon absorption and scattering of biological tissues, it is challenging to realize in vivo deep optical detections, particularly… read more here.
Keywords: detection deep; spectroscopy; detection; transmission raman ... See more keywords
Calibration Transfer of a Quantitative Transmission Raman PLS Model: Direct Transfer vs. Global Modeling
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-017-9299-4
Abstract: Global regulatory agencies have encouraged the use of process analytical technology (PAT) to assure quality in the pharmaceutical industry. A frequently cited obstacle to the implementation of spectroscopy-based PAT methods is the difficulty associated with… read more here.
Keywords: transmission raman; model; calibration; spectroscopy ... See more keywords
Analytical Method Development Using Transmission Raman Spectroscopy for Pharmaceutical Assays and Compliance with Regulatory Guidelines—Part II: Practical Implementation Considerations
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-018-9350-0
Abstract: Transmission Raman spectroscopy is a relatively new technique for quantitative analysis of pharmaceutical products, either during manufacturing or as a finished product test. As with any new analytical tool, several requirements need to be met… read more here.
Keywords: transmission raman; method development; development; spectroscopy ... See more keywords
Transmission Raman Spectroscopic Quantification of Active Pharmaceutical Ingredient in Coated Tablets of Hot-Melt Extruded Amorphous Solid Dispersion
Sign Up to like & getrecommendations! Published in 2019 at "Applied Spectroscopy"
DOI: 10.1177/0003702819884994
Abstract: Transmission Raman spectroscopy is an emerging technique, capable of quantitative analysis of drug products nondestructively using a multivariate data analysis approach. We developed and validated a chemometric method to quantify the active pharmaceutical ingredient in… read more here.
Keywords: active pharmaceutical; transmission raman; pharmaceutical ingredient; spectroscopy ... See more keywords
Application of Transmission Raman Spectroscopy in Combination with Partial Least-Squares (PLS) for the Fast Quantification of Paracetamol
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051707
Abstract: In recent years, transmission Raman spectroscopy (TRS) has emerged as a potent new tool for rapid, nondestructive quantitation in pharmaceutical manufacturing. In order to expand the applicability of TRS and enhance its use in product… read more here.
Keywords: transmission raman; spectroscopy; partial least; raman spectroscopy ... See more keywords