Abstract 1420: The non-canonical role of Rb in enhancers and insulators
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1420
Abstract: Despite the great significance of the tumor suppressor Rb in cancer biology, the full spectrum of its binding pattern in human cells was yet to be established. Here, we report that rather than exclusively associating… read more here.
Keywords: bound promoters; role; bound; non canonical ... See more keywords
A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1009017
Abstract: TRIM5α is a key cross-species barrier to retroviral infection, with certain TRIM5 alleles conferring increased risk of HIV-1 infection in humans. TRIM5α is best known as a species-specific restriction factor that directly inhibits the viral… read more here.
Keywords: trim5; autophagy machinery; canonical role; non canonical ... See more keywords