Clinical implication of the circumferential crescents lesions in immunoglobulin A nephropathy：A single-center study of Han Chinese population.
Sign Up to like & getrecommendations! Published in 2021 at "Human pathology"
DOI: 10.1016/j.humpath.2021.09.003
Abstract: A crescentic lesion in renal biopsy could be segmental or circumferential, but the distribution and clinical implication of the circumferential crescents in immunoglobulin A nephropathy (IgAN) remains unknown. A total of 384 crescentic IgAN patients… read more here.
Keywords: immunoglobulin nephropathy; clinical implication; circumferential crescent; circumferential crescents ... See more keywords
High levels of urinary complement proteins are associated with chronic renal damage and proximal tubule dysfunction in immunoglobulin A nephropathy
Sign Up to like & getrecommendations! Published in 2019 at "Nephrology"
DOI: 10.1111/nep.13477
Abstract: Complement activation is involved in the pathogenesis and progression of immunoglobulin A nephropathy (IgAN); however, the clinical implication of abnormal complement protein levels in serum and urine is not clear. To address this we analyzed… read more here.
Keywords: immunoglobulin nephropathy; high levels; complement; complement proteins ... See more keywords
Clinical course of Immunoglobulin A nephropathy with Crescents in a multi-ethnic Southeast Asian cohort.
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology"
DOI: 10.1111/nep.13723
Abstract: INTRODUCTION Clinical presentation and course of Immunoglobulin A nephropathy vary by ethnicity and geography and significance of extracapillary proliferation or crescents (IgAN-C) in Southeast Asia is not well described. We aimed to describe the clinical… read more here.
Keywords: course immunoglobulin; immunoglobulin nephropathy; igan; clinical course ... See more keywords
Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.141289
Abstract: IgA nephropathy (IgAN) is a leading cause of kidney failure, yet little is known about the immunopathogenesis of this disease. IgAN is characterized by deposition of IgA in the kidney glomeruli, but the source and… read more here.
Keywords: nephropathy characterized; immune responses; immunoglobulin nephropathy; specific iga ... See more keywords
Development and validation of diagnostic models for immunoglobulin A nephropathy based on gut microbes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1059692
Abstract: Background Immunoglobulin A nephropathy (IgAN) is a highly prevalent glomerular disease. The diagnosis potential of the gut microbiome in IgAN has not been fully evaluated. Gut microbiota, serum metabolites, and clinical phenotype help to further… read more here.
Keywords: gut; gut microbiota; diagnosis; immunoglobulin nephropathy ... See more keywords
Integrated Fecal Microbiome and Serum Metabolomics Analysis Reveals Abnormal Changes in Rats with Immunoglobulin A Nephropathy and the Intervention Effect of Zhen Wu Tang
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.606689
Abstract: Immunoglobulin A nephropathy (IgAN), an autoimmune renal disease with complicated pathogenesis, is one of the principal reasons for end-stage renal disease in the clinic. Evidence has linked apparent alterations in the components of the microbiome… read more here.
Keywords: immunoglobulin nephropathy; serum; microbiome; zhen tang ... See more keywords