Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells
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DOI: 10.1016/j.celrep.2019.05.078
Abstract: Summary Cohesin exists in two variants carrying either STAG/SA1 or SA2. Here we have addressed their specific contributions to the unique spatial organization of the mouse embryonic stem cell genome, which ensures super-enhancer-dependent transcription of… read more here.
Keywords: polycomb domains; cohesin; cohesin sa2; embryonic stem ... See more keywords
Defining the Boundaries of Polycomb Domains in Drosophila
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DOI: 10.1534/genetics.120.303642
Abstract: Polycomb group (PcG) genes are an important group of epigenetic regulators that act to repress transcription. In Drosophila, the PcG group protein complex PRC2 is recruited to discrete DNA elements called Polycomb response elements. PRC2… read more here.
Keywords: polycomb domain; transcription; polycomb domains; boundaries polycomb ... See more keywords