TDP‐43 Pathology Exacerbates Cognitive Decline in Primary Age‐Related Tauopathy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26438
Abstract: Primary age‐related tauopathy (PART) refers to tau neurofibrillary tangles restricted largely to the medial temporal lobe in the absence of significant beta‐amyloid plaques. PART has been associated with cognitive impairment, but contributions from concomitant limbic… read more here.
Keywords: tdp pathology; age related; primary age; related tauopathy ... See more keywords
“Education cannot cease”: the experiences of parents of primary age children (age 4-11) in Northern Ireland during school closures due to COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Educational Review"
DOI: 10.1080/00131911.2021.1974821
Abstract: This paper reports the research findings from an online survey of parents of primary-age pupils in Northern Ireland during the COVID-19 pandemic. The aims of the study were to explore how parents supported their child/ren’s… read more here.
Keywords: primary age; northern ireland; age; school ... See more keywords
TDP-43 and tau concurrence in the entorhinal subfields in primary age-related tauopathy and preclinical Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2023 at "Brain pathology"
DOI: 10.1111/bpa.13159
Abstract: Phosphorylated tau (p-tau) pathology correlates strongly with cognitive decline and is a pathological hallmark of Alzheimer's Disease (AD). In recent years, phosphorylated transactive response DNA-binding protein (pTDP-43) has emerged as a common comorbidity, found in… read more here.
Keywords: tau; primary age; alzheimer disease; pathology ... See more keywords
Primary age‐related tauopathy in a Finnish population‐based study of the oldest old (Vantaa 85+)
Sign Up to like & getrecommendations! Published in 2021 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12788
Abstract: Few studies have investigated primary age‐related tauopathy (PART) in a population‐based setting. Here, we assessed its prevalence, genetic background, comorbidities and features of cognitive decline in an unselected elderly population. read more here.
Keywords: population based; related tauopathy; age related; population ... See more keywords
Primary Age-Related Tauopathy in Human Subcortical Nuclei
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00529
Abstract: The present study aimed to determine the spatial distribution patterns of hyperphosphorylated tau-immunoreactive cells in subcortical nuclei of post-mortem human brain with primary age-related tauopathy (PART). Subcortical tauopathy has important pathological and clinical implications. Expression… read more here.
Keywords: primary age; part; age related; subcortical nuclei ... See more keywords