TCTP as a therapeutic target in melanoma treatment
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.230
Abstract: Background:Translationally controlled tumour protein (TCTP) is an antiapoptotic protein highly conserved through phylogeny. Translationally controlled tumour protein overexpression was detected in several tumour types. Silencing TCTP was shown to induce tumour reversion. There is a… read more here.
Keywords: melanoma; target melanoma; tctp; melanoma treatment ... See more keywords
PTEN as a target in melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2021-208008
Abstract: PTEN is a well-known tumour suppressor protein that is frequently found to be mutated, inactivated or deleted in a wide range of different cancers. Its tumour suppressive properties result predominantly from its inhibitory effects on… read more here.
Keywords: target melanoma; pten target; pathology; melanoma ... See more keywords
Fucosyltransferase 8 as a driver of melanoma metastasis: a new target for melanoma therapy?
Sign Up to like & getrecommendations! Published in 2017 at "Translational cancer research"
DOI: 10.21037/16284
Abstract: Protein glycosylation is a complex post-translational modification process, often affecting protein folding and function, but it has not been well understood due to the lack of effective tools for the study of this process. read more here.
Keywords: fucosyltransferase driver; driver melanoma; new target; melanoma metastasis ... See more keywords
Selected Flavonoids to Target Melanoma: A Perspective in Nanoengineering Delivery Systems
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9070290
Abstract: Melanoma is a complex type of cancer that depends on several metabolic factors, while the currently used therapies are not always effective and have unwanted side effects. In this review, the main factors involved in… read more here.
Keywords: target melanoma; selected flavonoids; perspective nanoengineering; nanoengineering delivery ... See more keywords