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Published in 2018 at "Advanced Drug Delivery Reviews"
DOI: 10.1016/j.addr.2018.01.006
Abstract: Abstract In order to maintain a smooth optical surface the corneal epithelium has to continuously renew itself so as to maintain its function as a barrier to fluctuating external surroundings and various environmental insults. After…
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Keywords:
therapeutic prospects;
wound healing;
corneal;
healing eye ... See more keywords
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Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119458
Abstract: Autoimmune diseases (ADs) are a class of chronic disease conditions with impaired tolerance to autoantigens. Currently, there is no effective treatment for ADs, and the existing medications have limitations due to non-specific targets and side…
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Keywords:
extracellular vesicles;
therapeutic prospects;
autoimmune diseases;
stem cells ... See more keywords
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1
Published in 2019 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2019.02.001
Abstract: Friedreich's ataxia (FRDA) is a progressive disease affecting multiple organs that is caused by systemic insufficiency of the mitochondrial protein frataxin. Current therapeutic strategies aim to elevate frataxin levels and/or alleviate the consequences of frataxin…
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Keywords:
friedreich ataxia;
therapeutic prospects;
prospects friedreich;
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Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.998748
Abstract: Since the end of 2019, COVID-19 caused by SARS-CoV-2 has spread worldwide, and the understanding of the new coronavirus is in a preliminary stage. Currently, immunotherapy, cell therapy, antiviral therapy, and Chinese herbal medicine have…
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Keywords:
coronavirus;
cernas covid;
therapeutic prospects;
prospects cernas ... See more keywords
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Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.879111
Abstract: Ovarian cancer (OC) is ranked as the leading cause of death among cancers of the female reproductive tract. First-line platinum treatment faces the severe challenges associated with the patient relapse and poor prognosis. Thus, it…
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Keywords:
polysaccharides ovarian;
ovarian cancer;
prospects polysaccharides;
therapeutic prospects ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1090237
Abstract: RNA interference has become increasingly used for genetic therapy following the rapid development of oligonucleotide drugs. Significant progress has been made in its delivery system and implementation in the treatment of target organs. After a…
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Keywords:
prospects acetylgalactosamine;
sirna conjugates;
sirna;
therapeutic prospects ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031731
Abstract: The interleukin-1 receptor type 1 (IL-1R1) holds pivotal roles in the immune system, as it is positioned at the “epicenter” of the inflammatory signaling networks. Increased levels of the cytokine IL-1 are a recognized feature…
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Keywords:
system;
disease;
central nervous;
therapeutic prospects ... See more keywords
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Published in 2023 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13060930
Abstract: A number of key insights into eye disease have been revealed in the past decade, which has resulted in the development of novel, effective, targeted therapies such as teprotumumab for the treatment of thyroid eye…
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Keywords:
challenges therapeutic;
therapeutic prospects;
prospects eye;
eye ... See more keywords