Association testing of vasopressin receptor 1a microsatellite polymorphisms in non‐clinical autism spectrum phenotypes
Sign Up to like & getrecommendations! Published in 2017 at "Autism Research"
DOI: 10.1002/aur.1716
Abstract: Variation in the AVPR1a gene, which codes for a receptor for the neurohormone vasopressin, has been found to relate to autism risk. Interestingly, variation in this gene also relates to differences in social behaviour in… read more here.
Keywords: research; autism; rs3; non clinical ... See more keywords
Uncovering the brain‐wide pattern of synaptic input to vasopressin‐expressing neurons in the paraventricular nucleus of the hypothalamus
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25476
Abstract: Arginine vasopressin (AVP) is a neuropeptide critical for the mammalian stress response and social behavior. AVP produced in the hypothalamus regulates water osmolality and vasoconstriction in the body, and in the brain, it regulates social… read more here.
Keywords: vasopressin; brain; expressing neurons; social behavior ... See more keywords
Expanding the role of vasopressin antagonism in polycystic kidney diseases: From adults to children?
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3672-x
Abstract: Polycystic kidney disease (PKD) encompasses a group of genetic disorders that are common causes of renal failure. The two classic forms of PKD are autosomal recessive polycystic kidney disease (ARPKD) and autosomal dominant polycystic kidney… read more here.
Keywords: kidney; kidney disease; polycystic kidney; adpkd patients ... See more keywords
Effect of Vasopressin V1b Receptor Blockade on Activity of the Hypothalamic—Pituitary—Adrenal Axis in Old Monkeys with Depression-Like and Anxious Behavior Subjected to Stress or Injected with Vasopressin
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4294-4
Abstract: The effect of selective antagonist of the arginine vasopressin (AVP) V1b receptors on the secretion of ACTH and corticosteroids in response to insulin-induced hypoglycemia and injection of AVP is studied in old Macaca mulatta females… read more here.
Keywords: anxious behavior; v1b; like anxious; depression like ... See more keywords
Vasopressin in Patients with Septic Shock and Dynamic Left Ventricular Outflow Tract Obstruction
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-020-06998-8
Abstract: Purpose Left ventricular outflow tract obstruction (LVOTO) is a relatively uncommon but severe condition that may lead to hemodynamic impairment. It can be elicited by morphological (left ventricular hypertrophy, sigmoid septum, prominent papillary muscle, prolonged… read more here.
Keywords: lvoto; ventricular outflow; septic shock; left ventricular ... See more keywords
Dual Vasopressin Receptor Antagonism to Improve Congestion in Patients With Acute Heart Failure: Design of the AVANTI Trial.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cardiac failure"
DOI: 10.1016/j.cardfail.2020.10.007
Abstract: BACKGROUND Loop diuretics are the main treatment for patients with acute heart failure (HF) but are associated with neurohormonal stimulation and worsening renal function and do not improve long-term outcomes. Antagonists to arginine vasopressin may… read more here.
Keywords: patients acute; heart failure; acute heart; failure ... See more keywords
HYPONATREMIA SECONDARY TO VASOPRESSIN IN AN ECMO DEPENDENT PATIENT WITH SEVERE ARDS DUE TO COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.07.636
Abstract: TOPIC: Critical Care TYPE: Fellow Case Reports INTRODUCTION: Vasopressin infusion induced hyponatremia is a rare phenomenon. It occurs especially when vasopressin is utilized as an adjunct vasopressor in non-septic shock states. 1 CASE PRESENTATION: 35-year-old… read more here.
Keywords: hyponatremia; infusion; vasopressin infusion; patient ... See more keywords
Development of a radioligand for imaging V1a vasopressin receptors with PET.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.08.037
Abstract: A series of vasopressin receptor V1a ligands have been synthesized for positron emission tomography (PET) imaging. The lead compound (1S,5R)-1 ((4-(1H-indol-3-yl)-3-methoxyphenyl) ((1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)methanone) and its F-ethyl analog 6c exhibited the best combination of high binding affinity… read more here.
Keywords: vasopressin receptors; v1a vasopressin; radioligand imaging; development radioligand ... See more keywords
(Re-)activity in the caregiving situation: Genetic diversity within Oxytocin–Vasopressin Pathway is associated with salivary oxytocin and vasopressin concentrations in response to contact with a crying infant-simulator
Sign Up to like & getrecommendations! Published in 2021 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2021.105294
Abstract: Oxytocin (OT) and vasopressin (AVP) hormones as well as their receptors (OXTR and AVPR1a) have been deemed crucial for caregiving and sensitive responsiveness to infant cues. However, previous research on genetic polymorphisms and OT and… read more here.
Keywords: caregiving situation; oxytocin vasopressin; avp levels; vasopressin ... See more keywords
Intranasal oxytocin, but not vasopressin, augments neural responses to toddlers in human fathers
Sign Up to like & getrecommendations! Published in 2017 at "Hormones and Behavior"
DOI: 10.1016/j.yhbeh.2017.01.006
Abstract: Abstract This study investigates paternal brain function with the hope of better understanding the neural basis for variation in caregiving involvement among men. The neuropeptides oxytocin (OT) and vasopressin (AVP) are implicated in paternal caregiving… read more here.
Keywords: human fathers; oxytocin vasopressin; intranasal oxytocin; function ... See more keywords
Discovery of Potent, Selective, and Short-Acting Peptidic V2 Receptor Agonists.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b00132
Abstract: The vasopressin analogue desmopressin (desamino-d-arginine8 vasopressin, dDAVP, 1) is a potent vasopressin 2 (V2) receptor (V2R) agonist approved in many countries for the treatment of diabetes insipidus, primary nocturnal enuresis, nocturia, and coagulation disorders. Since… read more here.
Keywords: potent selective; selective short; acting peptidic; receptor ... See more keywords