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Metagenomic shotgun sequencing to identify specific human gut microbes associated with immune checkpoint therapy efficacy in melanoma patients.

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9516Background: Immune checkpoint inhibitor therapy, ICT, achieves durable remissions in 30-50% of patients (pts) with metastatic melanoma (Larkin et al. NEJM 2015). It is still unclear what host f... Click to show full abstract

9516Background: Immune checkpoint inhibitor therapy, ICT, achieves durable remissions in 30-50% of patients (pts) with metastatic melanoma (Larkin et al. NEJM 2015). It is still unclear what host f...

Keywords: melanoma; immune checkpoint; shotgun sequencing; metagenomic shotgun; checkpoint; therapy

Journal Title: Journal of Clinical Oncology
Year Published: 2017

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