Topical application of recombinant activated factor VII during cesarean delivery for placenta previa
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2017.02.024
Abstract: BACKGROUND: During cesarean delivery in patients with placenta previa, hemorrhaging after removal of the placenta is often challenging. In this condition, the extraordinarily high concentration of tissue factor at the placenta site may constitute a… read more here.
Keywords: factor vii; activated factor; placenta; factor ... See more keywords
Off-label Use of Recombinant Activated Factor VII for Cardiac Surgical Bleeding.
Sign Up to like & getrecommendations! Published in 2023 at "Anesthesiology"
DOI: 10.1097/aln.0000000000004569
Abstract: Recombinant activated factor VII has been widely used in an off-label manner for cardiac surgical bleeding. Recent reports have administered recombinant activated factor VII earlier in the course of bleeding and at lower doses than… read more here.
Keywords: cardiac surgical; recombinant activated; activated factor; factor vii ... See more keywords
Emicizumab‐mediated haemostatic function in patients with haemophilia A is down‐regulated by activated protein C through inactivation of activated factor V
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Haematology"
DOI: 10.1111/bjh.15525
Abstract: Activated protein C (APC) inactivates activated factor V (FVa) and moderates FVIIIa by restricting FV cofactor function. Emicizumab is a humanized anti‐FIXa/FX bispecific monoclonal antibody that mimicks FVIIIa cofactor function. In recent clinical trials in… read more here.
Keywords: protein; activated factor; activated protein; inactivation ... See more keywords
Recombinant activated factor seven in pediatric cardiac surgery-does thrombotic risk outweigh hemostatic benefit?
Sign Up to like & getrecommendations! Published in 2019 at "Translational pediatrics"
DOI: 10.21037/tp.2019.10.04
Abstract: Therapies employed to attenuate perioperative bleeding following cardiopulmonary bypass (CPB) in children include antifibrinolytic therapy, allogenic blood product transfusion, and recombinant factor concentrates. Recombinant activated factor seven (rFVIIa) (Novoseven RT, Novo Nordisk A/S, Denmark) is… read more here.
Keywords: factor seven; activated factor; seven pediatric; pediatric cardiac ... See more keywords
Recombinant Activated Factor VII in Aortic Surgery for Patients Under Hypothermic Circulatory Arrest
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s352609
Abstract: Purpose We aimed to identify the risk factors of critical bleeding and investigate the safety of recombinant activated factor VII (rFVIIa) in aortic surgery under hypothermic circulatory arrest (HCA). Patients and Methods The present single-center… read more here.
Keywords: activated factor; factor vii; surgery; recombinant activated ... See more keywords