Interferon-γ Involvement in the Neuroinflammation Associated with Parkinson's Disease and L-DOPA-Induced Dyskinesia.
Sign Up to like & getrecommendations! Published in 2021 at "Neurotoxicity research"
DOI: 10.1007/s12640-021-00345-x
Abstract: Interferon-γ (IFN-γ) is a proinflammatory cytokine that activates glial cells. IFN-γ is increased in the plasma and brain of Parkinson's disease patients, suggesting its potential role in the disease. We investigated whether the IFN-γ deficiency… read more here.
Keywords: ifn mice; ifn; disease; dopa induced ... See more keywords
03.26 Early mouse interferon-alpha1 overexpression in vivo triggers an expansion of highly suppressive regulatory t lymphocytes protecting against experimental arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2016-211049.26
Abstract: Background Type I interferons (IFN-I) can be both anti- and pro-inflammatory. Their role is controversial in rheumatoid arthritis (RA) and experimental models. A not-understood IFN-I signature has been reported in RA patients. In mice, IFN-I… read more here.
Keywords: protection; ifn mice; ifn; arthritis ... See more keywords
IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler’s Murine Encephalomyelitis Viruses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.786940
Abstract: Type I Interferons (IFN-I) are important inducers of the antiviral immune response and immune modulators. IFN-β is the most highly expressed IFN-I in the central nervous system (CNS). The infection of SJL mice with the… read more here.
Keywords: c57bl mice; ifn mice; demyelinating disease; mice ... See more keywords