Innate immune signaling and immunothrombosis: New insights and therapeutic opportunities
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DOI: 10.1002/eji.202149410
Abstract: Activation of the coagulation cascade is a critical, evolutionarily conserved mechanism that maintains hemostasis by rapidly forming blood clots in response to blood‐borne infections and damaged blood vessels. Coagulation is a key component of innate… read more here.
Keywords: signaling immunothrombosis; coagulation; immune signaling; immunothrombosis new ... See more keywords
Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250010
Abstract: Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID‐19) pandemic. Neutrophils play a vital role in the immunopathology of… read more here.
Keywords: activation; traps nets; extracellular traps; neutrophil extracellular ... See more keywords
Mechanisms of immunothrombosis in COVID-19
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DOI: 10.1097/moh.0000000000000666
Abstract: Purpose of review Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus-2. Over the past year, COVID-19 has posed a significant threat to global health. Although the infection is… read more here.
Keywords: mechanisms immunothrombosis; immunothrombosis covid; covid induced; platelet ... See more keywords
COVID‐19 and immunothrombosis: emerging understanding and clinical management
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DOI: 10.1111/bjh.17664
Abstract: The COVID‐19 pandemic has been the most significant health crisis in recent global history. Early studies from Wuhan highlighted COVID‐19‐associated coagulopathy and a significant association with mortality was soon recognised. As research continues across the… read more here.
Keywords: immunothrombosis; covid immunothrombosis; covid; understanding clinical ... See more keywords
Staphylococcus aureus and Neutrophil Extracellular Traps: The Master Manipulator Meets Its Match in Immunothrombosis
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DOI: 10.1161/atvbaha.121.316930
Abstract: Over the past 10 years, neutrophil extracellular traps (NETs) have become widely accepted as an integral player in immunothrombosis, due to their complex interplay with both pathogens and components of the coagulation system. While the… read more here.
Keywords: extracellular traps; neutrophil extracellular; staphylococcus aureus; aureus ... See more keywords
NETosis and Neutrophil Extracellular Traps in COVID-19: Immunothrombosis and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.838011
Abstract: Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial mechanism of COVID-19 immunopathy is the recruitment and activation of neutrophils at the… read more here.
Keywords: sars cov; covid; immunothrombosis; neutrophil extracellular ... See more keywords
Mechanisms of Immunothrombosis by SARS-CoV-2
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DOI: 10.3390/biom11111550
Abstract: SARS-CoV-2 contains certain molecules that are related to the presence of immunothrombosis. Here, we review the pathogen and damage-associated molecular patterns. We also study the imbalance of different molecules participating in immunothrombosis, such as tissue… read more here.
Keywords: immunothrombosis sars; sars cov; immunothrombosis; mechanisms immunothrombosis ... See more keywords
Evolutionary Insight into Immunothrombosis as a Healing Mechanism
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DOI: 10.3390/ijms23158346
Abstract: Both invertebrates and vertebrates possess a cluster of immediate and local wound-sealing, pathogen-killing, and tissue healing responses known as immunoclotting and immunothrombosis, respectively, to cope with two life-threatening emergencies, namely, bleeding and microbial invasion. Despite… read more here.
Keywords: evolutionary insight; healing mechanism; insight immunothrombosis; immunothrombosis healing ... See more keywords