Skeletal muscle and adipose tissue changes in the first phase of treatment of pediatric solid tumors
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3584
Abstract: Body composition is increasingly recognized as an important factor in cancer outcomes. Use of computed tomography (CT) in cancer care provides the opportunity to accurately quantify whole‐body lean and adipose tissues from images at the… read more here.
Keywords: pediatric solid; skeletal muscle; body composition; tissue ... See more keywords
Advances in the treatment of pediatric solid tumors: A 50‐year perspective
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.27038
Abstract: In the United States, more than 10 000 cancers occur annually in children aged 0–14 years, and more than 5000 in adolescents aged 15–19. In the last 50 years, significant advances have been made in imaging,… read more here.
Keywords: treatment pediatric; advances treatment; pediatric solid; tumors year ... See more keywords
Progress toward liquid biopsies in pediatric solid tumors
Sign Up to like & getrecommendations! Published in 2019 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-019-09825-1
Abstract: Pediatric solid tumors have long been known to shed tumor cells, DNA, RNA, and proteins into the blood. Recent technological advances have allowed for improved capture and analysis of these typically scant circulating materials. Efforts… read more here.
Keywords: pediatric solid; liquid biopsies; solid tumors; toward liquid ... See more keywords
Mechanisms of Efficacy of the FGFR1–3 Inhibitor AZD4547 in Pediatric Solid Tumor Models
Sign Up to like & getrecommendations! Published in 2020 at "Investigational New Drugs"
DOI: 10.1007/s10637-020-00933-2
Abstract: Children with aggressive pediatric solid tumors have poor outcomes and novel treatments are needed. Pediatric solid tumors demonstrate aberrant expression and activity of the fibroblast growth factor receptor (FGFR) family, suggesting FGFR inhibitors may be… read more here.
Keywords: pediatric solid; inhibitor; solid tumor; efficacy ... See more keywords
Platelet Normalized Serum Vascular Endothelial Growth Factor Levels in Progressive Pediatric Solid Malignancies
Sign Up to like & getrecommendations! Published in 2020 at "Indian Pediatrics"
DOI: 10.1007/s13312-020-2081-6
Abstract: We read with interest the recently published article by Pramanik, et al. [1]. The study reported inconsistent trends in serum vascular endothelial growth factor (VEGF) and thrombospondin-1 (TSP1) in 108 patients with progressive pediatric solid… read more here.
Keywords: pediatric solid; serum vascular; vascular endothelial; endothelial growth ... See more keywords
Various checkpoint molecules, and tumor-infiltrating lymphocytes in common pediatric solid tumors: Possibilities for novel immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2019.1578843
Abstract: Abstract Long-term survival rates for pediatric patients with cancer have significantly improved, but novel approaches are desired for those with refractory/relapsed solid tumors. Recently, programed cell death-1/programed cell death-ligand-1 blockade has emerged as an effective… read more here.
Keywords: pediatric solid; solid tumors; checkpoint molecules; herpes virus ... See more keywords
Return to School and COVID-19 Vaccination for Pediatric Solid Organ Transplant Recipients in the United States: Expert Opinion for 2021-2022.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piab098
Abstract: The COVID-19 pandemic continues to generate challenges for pediatric solid organ transplant (SOT) recipients and their families. As rates of COVID-19 fluctuate, new SARS-CoV-2 variants emerge, and adherence to and implementation of mitigation strategies vary… read more here.
Keywords: pediatric solid; organ transplant; solid organ; school ... See more keywords
New developments in immunotherapy for pediatric solid tumors
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000000564
Abstract: Purpose of review Building upon preclinical advances, we are uncovering immunotherapy strategies that are translating into improved outcomes in tumor subsets. Advanced pediatric solid tumors carry poor prognoses and resultant robust efforts to apply immunotherapy… read more here.
Keywords: pediatric solid; solid tumors; immunotherapy pediatric; new developments ... See more keywords
Immunotherapy approaches for rare pediatric solid tumors: advances and future directions
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001206
Abstract: Purpose of review Immunotherapy for pediatric tumors is rapidly evolving. From major successes in pediatric hematologic malignancies, immunotherapy utility increased in the pediatric solid tumor landscape. Numerous pediatric solid tumors are defined as rare with… read more here.
Keywords: pediatric rare; pediatric solid; immunotherapy approaches; solid tumors ... See more keywords
Epidemiology and long‐term outcomes of cytomegalovirus DNAemia and disease in pediatric solid organ transplant recipients
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16822
Abstract: Despite prevention strategies, cytomegalovirus (CMV) remains a common infection in pediatric solid organ transplant recipients (SOTR). We sought to determine the frequency, associations with, and long‐term outcomes of CMV DNAemia in pediatric SOTR. We performed… read more here.
Keywords: epidemiology; pediatric solid; dnaemia; transplant recipients ... See more keywords
Antiviral toxicities in pediatric solid organ transplant recipients
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.17171
Abstract: Prophylaxis with valganciclovir (VGCV) is used routinely to prevent cytomegalovirus (CMV) infections in at‐risk pediatric solid organ transplant (SOT) recipients. However, the rate and factors associated with toxicities in this population are not well‐described. We… read more here.
Keywords: pediatric solid; vgcv prophylaxis; kidney injury; prophylaxis ... See more keywords