Trehalose‐6‐phosphate synthase influences polysaccharide synthesis and cell wall components in Ganoderma lucidum
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.202200279
Abstract: Trehalose‐6‐phosphate synthase (TPS) is a key enzyme that participates in trehalose metabolism, which can synthesize trehalose in a two‐step pathway with trehalose phosphatase, but its role in fungi is rarely studied, especially in large basidiomycetes.… read more here.
Keywords: cell; cell wall; trehalose phosphate; ganoderma lucidum ... See more keywords
Glucosamine-6-phosphate synthase inhibiting C3-β-cholesterol tethered spiro heterocyclic conjugates: Synthesis and their insight of DFT and docking study.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.102920
Abstract: A series of novel covalent cholesterol-spiro pyrrolidine/pyrrolizidine heterocyclic hybrids possessing biologically active oxindole, indanedione, and acenaphthylene-1-one have been synthesized by the reaction of C3-β-cholesteroalacrylate with heterocyclic di- and tri-ketones. All the sixteen compounds were obtained… read more here.
Keywords: phosphate synthase; glucosamine phosphate; study; cholesterol ... See more keywords
Involvement of trehalose‐6‐phosphate synthase in innate immunity of Musca domestica
Sign Up to like & getrecommendations! Published in 2019 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.10.010
Abstract: ABSTRACT Trehalose‐6‐phosphate synthase (TPS) is responsible for synthesizing trehalose, which is prevalent in crustaceans and insects as blood‐sugar. In this paper, a TPS gene from Musca domestica(MdTPS)has been cloned and characterized. MdTPS promoter was analyzed,… read more here.
Keywords: mdtps; musca domestica; trehalose phosphate; phosphate synthase ... See more keywords
Characterization and expression pattern of the trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase gene families in Populus.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.07.096
Abstract: Trehalose plays an important role in plant metabolism, growth development, and stress tolerance. Trehalose-6-phosphate synthase gene (TPS) and trehalose-6-phosphate phosphatase gene (TPP) are vital for the synthesis of trehalose. Populus is a prominent perennial woody… read more here.
Keywords: phosphate phosphatase; phosphate synthase; expression; trehalose phosphate ... See more keywords
The Significance of the Protein Interface Configuration for Allostery in Imidazole Glycerol Phosphate Synthase.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00332
Abstract: Imidazole glycerol phosphate synthase (ImGPS) from Thermotoga maritima is a model enzyme for studying allostery. The ImGPS complex consists of the cyclase subunit HisF and the glutaminase subunit HisH whose activity is stimulated by substrate… read more here.
Keywords: phosphate synthase; interface configuration; glycerol phosphate; imidazole glycerol ... See more keywords
Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00167
Abstract: It is important to understand how the catalytic activity of enzymes is related to their conformational flexibility. We have studied this activity-flexibility correlation using the example of indole-3-glycerol phosphate synthase from Sulfolobus solfataricus (ssIGPS), which… read more here.
Keywords: site loop; active site; phosphate synthase; glycerol phosphate ... See more keywords
Virtual screening of natural products against 5-enolpyruvylshikimate-3-phosphate synthase using the Anagreen herbicide-like natural compound library
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra02645g
Abstract: The shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) catalyzes a reaction involved in the production of amino acids essential for plant growth and survival. EPSPS is the main target of glyphosate, a broad-spectrum herbicide that acts… read more here.
Keywords: epsps; phosphate synthase; natural compound; herbicide ... See more keywords
In-silico studies on Myo inositol-1-phosphate synthase of Leishmania donovani in search of anti-leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1847194
Abstract: Abstract Myo-inositol is one of the vital nutritional requirements for the Leishmania parasites’ survival and virulence in the mammalian host. . Myo-inositol-1-phosphate synthase (MIPS) is responsible for the synthesis of myo-inositol in Leishmania, which plays… read more here.
Keywords: inositol phosphate; phosphate synthase; myo inositol; synthase ... See more keywords
Evaluation of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase (DAHPS) as a Vulnerable Target in Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00728-22
Abstract: Determining the vulnerability of a potential target allows us to assess whether its partial inhibition will impact bacterial growth. Here, we evaluated the vulnerability of the enzyme 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAHPS) from M. tuberculosis by… read more here.
Keywords: deoxy arabino; heptulosonate phosphate; tuberculosis; arabino heptulosonate ... See more keywords
Characterization of trehalose-6-phosphate synthase and Na+/H+ antiporter genes in Vuralia turcica and expression analysis under salt and cadmium stresses.
Sign Up to like & getrecommendations! Published in 2021 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202120200252
Abstract: Vuralia turcica (Fabaceae; Papilionoideae) is a critically endangered endemic plant species in Turkey. This plant grows naturally in saline environments, although the photosynthesis and physiological functions of many plants are affected by salt stress. Molecular… read more here.
Keywords: salt; salt cadmium; phosphate synthase; vuralia turcica ... See more keywords
Insights on the Control of Yeast Single-Cell Growth Variability by Members of the Trehalose Phosphate Synthase (TPS) Complex
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.607628
Abstract: Single-cell variability of growth is a biological phenomenon that has attracted growing interest in recent years. Important progress has been made in the knowledge of the origin of cell-to-cell heterogeneity of growth, especially in microbial… read more here.
Keywords: single cell; cell; level; phosphate synthase ... See more keywords