iPSCs-based generation of vascular cells: reprogramming approaches and applications
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2730-7
Abstract: Recent advances in the field of induced pluripotent stem cells (iPSCs) research have opened a new avenue for stem cell-based generation of vascular cells. Based on their growth and differentiation potential, human iPSCs constitute a… read more here.
Keywords: cell; vascular cells; ipscs; generation ... See more keywords
Hydrophobe-substituted bPEI derivatives: boosting transfection on primary vascular cells
Sign Up to like & getrecommendations! Published in 2017 at "Science China Materials"
DOI: 10.1007/s40843-017-9030-7
Abstract: Gene therapy targeted to vascular cells represents a promising approach for prevention and treatment of pathological conditions such as intimal hyperplasia, in-stent and post-angioplasty restenosis. In this context, polymeric non-viral gene delivery systems are a… read more here.
Keywords: bpei derivatives; vascular cells; transfection; primary vascular ... See more keywords
Layered double hydroxide nanoparticles: Impact on vascular cells, blood cells and the complement system.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.10.069
Abstract: The mounting interest in layered double hydroxide (LDH) nanoparticles as drug carriers and bio-imaging contrast agents makes biosafety evaluation of LDH essential. Considering the important role of blood circulation in bio-distribution of nanoparticles, the present… read more here.
Keywords: layered double; vascular cells; cells blood; blood ... See more keywords
Organization of Vascular Cells in the Haustorium of the Parasitic Flowering Plant Cuscuta japonica
Sign Up to like & getrecommendations! Published in 2018 at "Plant and Cell Physiology"
DOI: 10.1093/pcp/pcx197
Abstract: The stem parasite dodder, Cuscuta japonica, has evolved a specialized root-like organ, the haustorium, which is differentiated from the stem. In order to take up water and nutrients, C. japonica reprograms haustorial cells to vascular… read more here.
Keywords: xylem; cuscuta japonica; plant; vascular cells ... See more keywords
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner.
Sign Up to like & getrecommendations! Published in 2023 at "Protein & cell"
DOI: 10.1093/procel/pwad027
Abstract: Hypoxia-inducible factor (HIF-1α), a core transcription factor responding to changes in cellular oxygen levels, is closely associated with a wide range of physiological and pathological conditions. However, its differential impacts on vascular cells types and… read more here.
Keywords: regeneration; cell; vascular cells; human esc ... See more keywords
OLA1 Phosphorylation Governs the Mitochondrial Bioenergetic Function of Pulmonary Vascular Cells.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0186oc
Abstract: Mitochondrial function and metabolic homeostasis are integral to cardiovascular function and influence how vascular cells respond to stress. However, little is known regarding how mitochondrial redox control mechanisms and metabolic regulation interact in the developing… read more here.
Keywords: ola1 phosphorylation; function; vascular cells; mitochondrial bioenergetic ... See more keywords
Contribution of Vascular Cells to Neointimal Formation
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0168914
Abstract: The de-differentiation and proliferation of smooth muscle cells (SMCs) are widely accepted as the major contributor to vascular remodeling. However, recent studies indicate that vascular stem cells (VSCs) also play an important role, but their… read more here.
Keywords: neointimal formation; vascular cells; contribution; cre rosa ... See more keywords
Chromatin architecture around stroke haplotypes provides evidence that genetic risk is conferred through vascular cells.
Sign Up to like & getrecommendations! Published in 2022 at "Epigenomics"
DOI: 10.2217/epi-2021-0307
Abstract: Introduction: Genome-wide association studies (GWAS) have identified numerous stroke-associated SNPs. To understand how SNPs affect gene expression related to increased stroke risk, we studied epigenetic landscapes surrounding 26 common, validated stroke-associated loci. Methods: We mapped the… read more here.
Keywords: vascular cells; stroke associated; chromatin architecture; architecture around ... See more keywords
Nuclear Mechanosensation and Mechanotransduction in Vascular Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.905927
Abstract: Vascular cells are constantly subjected to physical forces associated with the rhythmic activities of the heart, which combined with the individual geometry of vessels further imposes oscillatory, turbulent, or laminar shear stresses on vascular cells.… read more here.
Keywords: vascular cells; nuclear mechanosensation; mechanosensation mechanotransduction; geometry ... See more keywords
Defective efferocytosis of vascular cells in heart disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1031293
Abstract: The efficient phagocytic clearance of dying cells and apoptotic cells is one of the processes that is essential for the maintenance of physiologic tissue function and homeostasis, which is termed “efferocytosis.” Under normal conditions, “find… read more here.
Keywords: defective efferocytosis; vascular cells; efferocytosis; efferocytosis vascular ... See more keywords
The Role of Vascular Cells in Pancreatic Beta-Cell Function
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.667170
Abstract: Insulin-producing β-cells constitute the majority of the cells in the pancreatic islets. Dysfunction of these cells is a key factor in the loss of glucose regulation that characterizes type 2 diabetes. The regulation of many… read more here.
Keywords: vascular cells; role vascular; pancreatic beta; cells pancreatic ... See more keywords