Targeting SCF E3 Ligases for Cancer Therapies.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-1025-0_9
Abstract: SKP1-cullin-1-F-box-protein (SCF) E3 ubiquitin ligase complex is responsible for the degradation of proteins in a strictly regulated manner, through which it exerts pivotal roles in regulating various key cellular processes including cell cycle and division,… read more here.
Keywords: scf ligases; biology; cancer; ligases cancer ... See more keywords
Emerging cancer therapies and cardiovascular risk
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02263-9
Abstract: The cardiovascular (CV) toxicity profiles of traditional cancer therapies such as anthracyclines and radiation therapy are familiar to many cardiologists. With the development and widespread use of additional cancer therapeutics, CV toxicities related to these… read more here.
Keywords: emerging cancer; cardiovascular risk; cancer; cancer therapies ... See more keywords
Patient-Centered Diabetes Care of Cancer Patients
Sign Up to like & getrecommendations! Published in 2021 at "Current Diabetes Reports"
DOI: 10.1007/s11892-021-01435-y
Abstract: Purpose of Review There is a bidirectional relationship between cancer and diabetes, with one condition influencing the prognosis of the other. Multiple cancer therapies cause diabetes including well-established medications such as glucocorticoids and novel cancer… read more here.
Keywords: cancer; centered diabetes; cancer therapies; patient centered ... See more keywords
Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies.
Sign Up to like & getrecommendations! Published in 2019 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2018.08.005
Abstract: DNA damage has been considered the primary action of ionizing radiation (IR) in normal and tumor cells resulting in cell autonomous death. However, recent findings have elucidated novel local and systemic effects of IR mediated… read more here.
Keywords: rna sensing; response; rna; stress ... See more keywords
Curcumin encapsulation in functional PLGA nanoparticles: A promising strategy for cancer therapies.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in colloid and interface science"
DOI: 10.1016/j.cis.2021.102582
Abstract: Nanoparticles have emerged as promising drug delivery systems for the treatment of several diseases. Novel cancer therapies have exploited these particles as alternative adjuvant therapies to overcome the traditional limitations of radio and chemotherapy. Curcumin… read more here.
Keywords: cancer; curcumin encapsulation; cancer therapies; plga nanoparticles ... See more keywords
Monoclonal antibody-based cancer therapies
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Chemical Engineering"
DOI: 10.1016/j.cjche.2020.11.009
Abstract: Abstract Targeted therapy has been widely demonstrated as an effective strategy to treat cancers, the leading cause of death in the world. This minireview summarizes the technical platforms and methodologies utilized to develop and engineer… read more here.
Keywords: antibody based; based cancer; antibody; cancer therapies ... See more keywords
Synthesis of clay based nanoagent for combined photothermal and photodynamic cancer therapies.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b19930
Abstract: Photo-induced cancer therapies, mainly including photothermal therapy (PTT) and photodynamic therapy (PDT), have attracted numerous attentions owing to the high selectivity, convenience, and few side effects. However, single PTT usually requires high laser power density,… read more here.
Keywords: synthesis clay; clay based; pdt; cancer ... See more keywords
Genomics-guided pre-clinical development of cancer therapies
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Cancer"
DOI: 10.1038/s43018-020-0067-x
Abstract: Since the approval of trastuzumab for the treatment of breast cancers more than two decades ago, many clinically effective targeted anti-cancer therapies have been developed. Here we consider the evidence that supports genomics-guided drug development… read more here.
Keywords: clinical development; genomics guided; pre clinical; cancer ... See more keywords
Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvac132
Abstract: Abstract Heart failure (HF) and cancer are the leading causes of death worldwide and accumulating evidence demonstrates that HF and cancer affect one another in a bidirectional way. Patients with HF are at increased risk… read more here.
Keywords: cancer; heart failure; targeted anti; mechanisms shared ... See more keywords
Fertility Preservation for Adolescents Receiving Cancer Therapies
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Obstetrics and Gynecology"
DOI: 10.1097/grf.0000000000000547
Abstract: According to the National Cancer Institute, ∼300,000 children globally are diagnosed with cancer each year. Advancements in chemotherapy and radiotherapy have revolutionized cancer treatment and improved long-term survival. Although many survivors will remain in good… read more here.
Keywords: cancer therapies; fertility preservation; preservation adolescents; cancer ... See more keywords
Tumour‐targeting bacteria‐based cancer therapies for increased specificity and improved outcome
Sign Up to like & getrecommendations! Published in 2017 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.12787
Abstract: ‘You have cancer’ – a devastating diagnosis that still strikes patients hard. Despite substantial improvements of standard therapies over the years, there is still no general cure available. Here, we review the revival of an… read more here.
Keywords: based cancer; bacteria based; targeting bacteria; tumour targeting ... See more keywords