Cholinergic anti‐inflammatory pathway confers airway protection against oxidative damage and attenuates inflammation in an allergic asthma model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29101
Abstract: Asthma is characterized by the influx of inflammatory cells, especially of eosinophils as well as reactive oxygen species (ROS) production, driven by the release of the T helper 2 (Th2)‐cell‐associated cytokines. The cholinergic anti‐inflammatory pathway… read more here.
Keywords: anti inflammatory; inflammation; inflammation allergic; inflammatory pathway ... See more keywords
Donepezil Prevents Inhibition of Cerebral Energetic Metabolism Without Altering Behavioral Parameters in Animal Model of Obesity
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03107-x
Abstract: Obesity is characterized by chronic inflammation of low grade. The cholinergic anti-inflammatory pathway favors the reduction of the inflammatory response. In this work the effect of stimulation of the cholinergic anti-inflammatory pathway on SHIRPA behavioral… read more here.
Keywords: anti inflammatory; donepezil; donepezil prevents; inflammatory pathway ... See more keywords
The cholinergic anti‐inflammatory pathway: an innovative treatment strategy for respiratory diseases and their comorbidities
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2017.12.003
Abstract: HighlightsThe cholinergic anti‐inflammatory pathway modulates inflammatory responses.The &agr;7nAChR is the critical target on inflammatory cells in this pathway.Recent studies newly revealed neuron‐ILC2s interactions in allergic inflammation.Neuroimmune interactions are potential therapeutic targets for lung diseases. &NA;… read more here.
Keywords: anti inflammatory; cholinergic anti; inflammatory responses; inflammatory pathway ... See more keywords
Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages: A possible link to the cholinergic anti-inflammatory pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2019.04.012
Abstract: The α7 nicotinic acetylcholine receptor (CHRNA7) modulates the inflammatory response by activating the cholinergic anti-inflammatory pathway. CHRFAM7A, the human-restricted duplicated form of CHRNA7, has a negative effect on the functioning of α7 receptors, suggesting that… read more here.
Keywords: anti inflammatory; chrfam7a; responsiveness lps; expression ... See more keywords
Vagus nerve stimulation enhances the cholinergic anti-inflammatory pathway to reduce lung injury in acute respiratory distress syndrome via STAT3
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00431-1
Abstract: The cholinergic anti-inflammatory pathway (CAIP) is important for antagonizing inflammation and treating several diseases, including acute respiratory distress syndrome (ARDS), and is related to vagus nerve integrity. However, its underlying pathophysiological mechanism is still unclear.… read more here.
Keywords: caip; cholinergic anti; pathway; vagus nerve ... See more keywords
Sevoflurane-induced inflammation development: involvement of cholinergic anti-inflammatory pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000507
Abstract: Chronic inflammation plays an important role in the mechanisms underpinning the development of anesthesia-induced cognitive dysfunction. However, less is known about how anesthesia causes inflammation. One possibility is that the inflammation is related to alteration… read more here.
Keywords: anti inflammatory; cholinergic anti; sevoflurane induced; inflammatory pathway ... See more keywords
AB0120 THE MECHANISM OF TRADITIONAL CHINESE MEDICINE PRESCRIPTION ER-MIAO-SAN IN THE TREATMENT OF RHEUMATOID ARTHRITIS BASED ON CHOLINERGIC ANTI-INFLAMMATORY PATHWAY
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.4774
Abstract: Background: Rheumatoid arthritis (RA) is a chronic progressive autoimmune disease. The traditional Chinese herbal formula Er-miao-san (EMS) has been used to treat RA demonstrating significant clinical efficacy; however, the mechanism of action remains unclear. In… read more here.
Keywords: anti inflammatory; medicine; treatment; arthritis ... See more keywords
Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis
Sign Up to like & getrecommendations! Published in 2020 at "Mediators of Inflammation"
DOI: 10.1155/2020/1320278
Abstract: Inflammatory storm is an important pathological mechanism of multiple organ dysfunction, and it is associated with most deaths in septic patients, deserving to be studied. Recent findings have confirmed that the Medullary Visceral Zone (MVZ)… read more here.
Keywords: anti inflammatory; sepsis; visceral zone; medullary visceral ... See more keywords
Role of Cholinergic Anti-Inflammatory Pathway in Protecting Sepsis-Induced Acute Lung Injury through Regulation of the Conventional Dendritic Cells
Sign Up to like & getrecommendations! Published in 2022 at "Mediators of Inflammation"
DOI: 10.1155/2022/1474891
Abstract: Background The cholinergic anti-inflammatory pathway connects the immune response system and the nervous system via the vagus nerve. The key regulatory receptor is the α7-subtype of the nicotinic acetylcholine receptor (α7nAChR). Cholinergic anti-inflammatory pathway has… read more here.
Keywords: anti inflammatory; inflammatory pathway; conventional dcs; cholinergic anti ... See more keywords
The cholinergic anti-inflammatory pathway in resistant hypertension treated with renal denervation
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine"
DOI: 10.1186/s10020-019-0097-y
Abstract: BackgroundRenal denervation (RDN) reduces sympathetic tone and may alter the sympathetic-parasympathetic balance. The autonomic nervous system is partly a regulator of innate immunity via the cholinergic anti-inflammatory pathway (CAP) which inhibits inflammation via the vagus… read more here.
Keywords: anti inflammatory; rdn; pathway; hypertension ... See more keywords
Cholinergic Anti-inflammatory Pathway and Stroke.
Sign Up to like & getrecommendations! Published in 2017 at "Current drug delivery"
DOI: 10.2174/1567201814666170201150015
Abstract: BACKGROUND Stroke is devastating cerebrovascular event which is responsible for 6.7 million deaths each year worldwide. Inflammation plays an important role in the pathophysiology of stroke. Targeting inflammation after stroke is highly actual topic for… read more here.
Keywords: anti inflammatory; cholinergic anti; inflammation; inflammatory pathway ... See more keywords