Rh-endostatin combined with chemotherapy in patients with advanced or recurrent mucosal melanoma: retrospective analysis of real-world data
Sign Up to like & getrecommendations! Published in 2021 at "Investigational New Drugs"
DOI: 10.1007/s10637-021-01172-9
Abstract: Background. Mucosal melanoma is rare and has distinct clinical and genetic features. Even with advances in targeted and immune therapies, the survival of patients with advanced or recurrent mucosal melanomas remains poor. The standard treatment… read more here.
Keywords: endostatin; mucosal melanoma; mucosal; recurrent mucosal ... See more keywords
Effect of endostatin on Wnt pathway of stem-like cells in bladder cancer in tumor microenvironment
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05487-3
Abstract: Wnt/β-catenin signaling pathway modulates miscellaneous biological events in cells including gene expression, cell growth, apoptosis, metabolism and transition. The aim of this study was to investigate the effect of endostatin on Wnt signaling pathway of… read more here.
Keywords: bladder cancer; endostatin; wnt; catenin ... See more keywords
Endostatin predicts mortality in patients with acute dyspnea - a cohort study of patients seeking care in emergency departments.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2019.10.004
Abstract: BACKGROUND Increased levels of circulating endostatin predicts cardiovascular morbidity and impaired kidney function in the general population. The utility of endostatin as a risk marker for mortality in the emergency department (ED) has not been… read more here.
Keywords: endostatin; acute dyspnea; mortality; emergency ... See more keywords
Consumption of whole grain/bran rye instead of refined wheat decrease concentrations of TNF-R2, e-selectin, and endostatin in an exploratory study in men with prostate cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2019.01.007
Abstract: BACKGROUND & AIMS Rye consumption has shown beneficial effects on prostate cancer tumors, as indicated by slower initial tumor growth in animal models and lowering of prostate-specific antigen (PSA) in humans. This study evaluated the… read more here.
Keywords: endostatin; prostate cancer; grain bran; cancer ... See more keywords
Efficacy and safety of continuous infusion of Rh-endostatin combined with platinum-based chemotherapy for advanced triple-negative breast cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of palliative medicine"
DOI: 10.21037/apm-21-2624
Abstract: BACKGROUND This study aimed to prospectively evaluate and investigate the efficacy and safety of recombinant human endostatin (Rh-endostatin) combined with platinum-based regimens for advanced triple-negative breast cancer (TNBC) patients. METHODS This study was a prospective,… read more here.
Keywords: efficacy safety; combined platinum; endostatin; platinum based ... See more keywords
Extended use of rh-endostatin improves prognosis in patients with advanced non-small cell lung cancer: an analysis of retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thoracic Disease"
DOI: 10.21037/jtd-22-1292
Abstract: Background Rh-endostatin is a potent inhibitor of angiogenesis approved and widely used for advanced non-small cell lung cancer (NSCLC) in China. While the efficacy and safety of extended use of rh-endostatin with platinum-based chemotherapy during… read more here.
Keywords: cell; endostatin; analysis; use endostatin ... See more keywords
Role Of Endostatin In Rheumatoid Arthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Current rheumatology reviews"
DOI: 10.2174/1573397115666191127141801
Abstract: Background- Endostatin by virtue of their therapeutic value against rheumatoid arthritis have recently generated enormous interest among biomedical science. Recent study revealed that various approaches have been made to prevent rheumatoid arthritis by either controlling… read more here.
Keywords: endostatin; endostatin rheumatoid; role endostatin; rheumatoid arthritis ... See more keywords
Endostatin induces normalization of blood vessels in colorectal cancer and promotes infiltration of CD8+ T cells to improve anti-PD-L1 immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.965492
Abstract: Introduction The purpose of this study was to evaluate recombinant human endostatin (rHE)-induced normalization of the tumor vasculature in colorectal cancer (CRC) and to evaluate the therapeutic effects of combined treatment with rHE and a… read more here.
Keywords: infiltration; endostatin; inhibitor; cd8 cells ... See more keywords
Increased plasma endostatin and GDF15 in indolent non-Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2023 at "Upsala Journal of Medical Sciences"
DOI: 10.48101/ujms.v128.9392
Abstract: Background Increased microvascular density correlates with more advanced disease and unfavorable overall survival in non-Hodgkin lymphoma (NHL), suggesting that angiogenesis is important for disease progression. However, studies of anti-angiogenic agents in NHL patients, have generally… read more here.
Keywords: endostatin; lymphoma; plasma endostatin; indolent ... See more keywords
Endostatin as a Biomarker of Basement Membrane Degradation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Atherosclerosis and Thrombosis"
DOI: 10.5551/jat.ed077
Abstract: Endostatin was originally isolated from murine hemangioendothelioma culture medium that inhibited tumor angiogenesis and growth, and biochemical analysis revealed it to be a C-terminal fragment of collagen XVIII. Collagen XVIII is a non-fibrillar collagen ubiquitously… read more here.
Keywords: endostatin; collagen xviii; atherosclerosis; basement membrane ... See more keywords