Infections after photodynamic therapy in Condyloma acuminatum patients: incidence and management
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-018-1623-0
Abstract: Condyloma acuminatum (CA), or genital wart, is a sexually transmitted infection caused by human papillomaviruses. Increasing evidences demonstrated that photodynamic therapy (PDT) is effective in eliminating latent HPV infection, the major reason for CA recurrence.… read more here.
Keywords: infection; group; acid group; condyloma acuminatum ... See more keywords
Wide dissemination of SCCfusC in fusidic acid-resistant coagulase-negative staphylococci and implication for its spread to methicillin-resistant staphylococcus aureus in Taiwan.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2018.01.020
Abstract: The fusidic acid (FUS) resistance determinants fusB, fusC, fusD and fusF in coagulase-negative staphylococci (CoNS) clinical isolates were examined. Among 208 FUS-resistant isolates, the fusB gene was the most common resistance determinant in each species,… read more here.
Keywords: staphylococcus; hominis; subsp hominis; hominis subsp ... See more keywords
3D-QSAR Modeling and Synthesis of New Fusidic Acid Derivatives as Antiplasmodial Agents
Sign Up to like & getrecommendations! Published in 2018 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00105
Abstract: Wide spread Plasmodium falciparum ( P. falciparum) resistance has compromised existing antimalarial therapies to varying degrees. Novel agents, able to circumvent antimalarial drug resistance, are therefore needed. Fusidic acid is a unique antibiotic with a… read more here.
Keywords: new fusidic; antiplasmodial activity; acid derivatives; acid ... See more keywords
Fusidic acid resistance through changes in the dynamics of the drug target
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2008577117
Abstract: Significance The World Health Organization has declared antimicrobial resistance one of the greatest threats to human health. Understanding the molecular mechanisms by which bacteria resist the effects of antibiotic therapies is central to understanding antimicrobial… read more here.
Keywords: dynamics drug; target; drug target; resistance ... See more keywords
A self-assembled polymer therapeutic for simultaneously enhancing solubility and antimicrobial activity and lowering serum albumin binding of fusidic acid
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1803140
Abstract: Abstract The global antimicrobial resistance crisis has prompted worldwide efforts to develop new and more efficient antimicrobial compounds, as well as to develop new drug delivery strategies and targeting mechanisms. This study aimed to synthesize… read more here.
Keywords: simultaneously enhancing; peg; solubility; activity ... See more keywords
Synthesis of fusidane triterpenoid Mannich bases as potential antibacterial and antitumor agents.
Sign Up to like & getrecommendations! Published in 2023 at "Natural product research"
DOI: 10.1080/14786419.2022.2163483
Abstract: Mannich bases (8 examples) were synthesized via aminomethylation of fusidane propargyl esters. In vitro antimicrobial screening against key ESKAPE pathogens showed that the fusidic acid based Mannich products exhibit a high antimicrobial effect against Gram-positive… read more here.
Keywords: fusidane; fusidane triterpenoid; synthesis fusidane; mannich bases ... See more keywords
Muscle Damage Due to Fusidic Acid–Statin Interaction: Review of 75 Cases From the French Pharmacovigilance Database and Literature Reports
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Therapeutics"
DOI: 10.1097/mjt.0000000000000679
Abstract: Background/Area of Uncertainty: Statins, which reduce cardiovascular risk in both primary and secondary prevention, are one of the most widely prescribed therapeutic classes in the world. Usually well-tolerated, statin-associated muscle symptoms are a well-known adverse… read more here.
Keywords: muscle; interaction; muscle damage; fusidic acid ... See more keywords
The Dissemination of Fusidic Acid Resistance Among Staphylococcus epidermidis Clinical Isolates in Wenzhou, China
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s365071
Abstract: Purpose Fusidic acid (FA), a potent steroidal antibiotic, is used topically to treat skin and soft tissue infections (SSTIs) caused by Staphylococci. The aim of this study is to report the prevalence of fusidic acid… read more here.
Keywords: epidermidis; epidermidis clinical; resistant epidermidis; staphylococcus epidermidis ... See more keywords
Cationic-bilayered nanoemulsion of fusidic acid: an investigation on eradication of methicillin-resistant Staphylococcus aureus 33591 infection in burn wound.
Sign Up to like & getrecommendations! Published in 2018 at "Nanomedicine"
DOI: 10.2217/nnm-2017-0227
Abstract: AIM The aim of the current study was to investigate the therapeutic efficacy of cationic-charged bilayered nanoemulsion for topical delivery of fusidic acid in eradicating methicillin-resistant Staphylococcus aureus (MRSA) bacterial burn wound infection. MATERIALS &… read more here.
Keywords: burn; burn wound; infection; bilayered nanoemulsion ... See more keywords
An unusual outbreak in the Netherlands: community-onset impetigo caused by a meticillin-resistant Staphylococcus aureus with additional resistance to fusidic acid, June 2018 to January 2020
Sign Up to like & getrecommendations! Published in 2022 at "Eurosurveillance"
DOI: 10.2807/1560-7917.es.2022.27.49.2200245
Abstract: In this retrospective observational study, we analysed a community outbreak of impetigo with meticillin-resistant Staphylococcus aureus (MRSA), with additional resistance to fusidic acid (first-line treatment). The outbreak occurred between June 2018 and January 2020 in… read more here.
Keywords: impetigo; resistance; fusidic acid; community onset ... See more keywords
Synthesis and Biological Evaluation of Novel Fusidic Acid Derivatives as Two-in-One Agent with Potent Antibacterial and Anti-Inflammatory Activity
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11081026
Abstract: Fusidic acid (FA), a narrow-spectrum antibiotics, is highly sensitive to various Gram-positive cocci associated with skin infections. It has outstanding antibacterial effects against certain Gram-positive bacteria whilst no cross-resistance with other antibiotics. Two series of… read more here.
Keywords: synthesis biological; aromatic derivatives; biological evaluation; anti inflammatory ... See more keywords