Prevalence and risk factors for hepatitis B and C viruses in patients with leprosy.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.04.024
Abstract: It has been reported a higher seroprevalence of HBV and HCV in leprosy patients than in the general population, but the reasons for these findings are not yet clear. On the other hand, there is… read more here.
Keywords: leprosy patients; hcv leprosy; hcv; risk factors ... See more keywords
A distinct double positive IL-17A+/F+ T helper 17 cells induced inflammation leads to IL17 producing neutrophils in Type 1 reaction of leprosy patients.
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2019.154873
Abstract: Type 1 reactions (T1R) an inflammatory condition, of local skin patches in 30-40% leprosy patients during the course of MDT. IL-17A and IL-17F play an important role in regulating skin inflammation through neutrophils. In the… read more here.
Keywords: 17a 17f; leprosy patients; double positive; producing neutrophils ... See more keywords
Characterization of ML0314c of Mycobacterium leprae and deciphering its role in the immune response in leprosy patients.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2017.12.001
Abstract: Mycobacterium leprae has a reduced genome size due to the reductive evolution over a long period of time. Lipid metabolism plays an important role in the life cycle and pathogenesis of this bacterium. In comparison… read more here.
Keywords: mycobacterium; response; leprosy patients; response leprosy ... See more keywords
Reduced vitamin D receptor (VDR) and cathelicidin antimicrobial peptide (CAMP) gene expression contribute to the maintenance of inflammatory immune response in leprosy patients.
Sign Up to like & getrecommendations! Published in 2022 at "Microbes and infection"
DOI: 10.1016/j.micinf.2022.104981
Abstract: Leprosy is an infectious disease influenced by genetic, immunological, and environmental factors. Reduced gene expressions may be associated with the immunological response pattern and leprosy susceptibility. We investigated the direct and indirect effects of Vitamin… read more here.
Keywords: response; leprosy patients; gene; camp gene ... See more keywords
Structural aspects of lesional and non-lesional skin microbiota reveal key community changes in leprosy patients from India
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80533-5
Abstract: Although skin is the primary affected organ in Leprosy, the role of the skin microbiome in its pathogenesis is not well understood. Recent reports have shown that skin of leprosy patients (LP) harbours perturbed microbiota… read more here.
Keywords: leprosy patients; microbiota; skin; non lesional ... See more keywords
Validation of a Simple Instrument of Fast Application to Track Disability in Leprosy Patients
Sign Up to like & getrecommendations! Published in 2022 at "Revista Brasileira de Ortopedia"
DOI: 10.1055/s-0042-1742342
Abstract: Objective To evaluate a simple and fast diagnostic instrument to be used by any health professional to track the disability presented by leprosy patients. Method Validation study of a diagnostic test performed in a sample… read more here.
Keywords: functional disability; disability; instrument; disability leprosy ... See more keywords
High seropositivity against NDO-LID in a group of household contacts of leprosy patients. Are we close to leprosy elimination in Colombia?
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens and global health"
DOI: 10.1080/20477724.2023.2217405
Abstract: INTRODUCTION Leprosy is a chronic infectious disease caused by two mycobacteria (Mycobacterium leprae and Mycobacterium lepromatosis). The household contacts (HHC) of leprosy index cases are at higher risk of being infected with these mycobacteria. Therefore,… read more here.
Keywords: household contacts; seropositivity; high seropositivity; leprosy patients ... See more keywords
Stigma, participation restriction and mental distress in patients affected by leprosy, cutaneous leishmaniasis and Chagas disease: a pilot study in two co-endemic regions of eastern Colombia
Sign Up to like & getrecommendations! Published in 2020 at "Transactions of the Royal Society of Tropical Medicine and Hygiene"
DOI: 10.1093/trstmh/trz132
Abstract: Abstract Background Leprosy, cutaneous leishmaniasis (CL) and Chagas disease (CD) are neglected tropical diseases with a high psychosocial burden (PSB). These conditions are endemic in Norte de Santander and Arauca in Colombia, but data on… read more here.
Keywords: mental distress; participation restriction; leprosy cutaneous; leprosy patients ... See more keywords
Elevated IL‐23 in skin promotes IL‐23 derived Th17 responses in leprosy patients
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13689
Abstract: Leprosy is an infectious disease caused by non‐cultivable bacteria Mycobacterium leprae. Th17 cells play vital roles during pathogenesis of leprosy reactions and IL‐23 is involved in Th17 cell differentiation. Although previous studies have reported the… read more here.
Keywords: skin promotes; elevated skin; promotes derived; derived th17 ... See more keywords
Risk Factors for Disability Upgrading Among Leprosy Patients During Treatment: Multilevel Modeling Analysis
Sign Up to like & getrecommendations! Published in 2022 at "SAGE Open Nursing"
DOI: 10.1177/23779608221129936
Abstract: Background Leprosy not only brings about bodily incapacity but also creates a nasty image of affected individuals, triggering discrimination and social stigma. The purpose of this study was to evaluate the status of leprosy disability… read more here.
Keywords: disability; factors disability; analysis; risk ... See more keywords
Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008746
Abstract: Leprosy is a stigmatizing, chronic infection which degenerates the nervous system and often leads to incapacitation. Multi-drug therapy which consists of dapsone, rifampicin and clofazimine has been effective to combat this disease. In Indonesia, especially… read more here.
Keywords: leprosy patients; biomarker; study; hla ... See more keywords